There's increasing talk of humans flying into deep space. Dennis Tito apparently proposes sending two people around Mars in a Dragon capsule. SpaceX talks about using a modified Dragon-- or perhaps tethering two Dragons together-- to settle Mars. The Obama administration wants to send a crew on a months long trip to an asteroid in the Orion capsule.
Let's get real. An interplanetary spaceship that will support a crew for months or years will have to be something the size of ISS or larger. That's the only way to get back a crew that is physically and emotionally healthy.